Epistasis Blog

From the Computational Genetics Laboratory at Dartmouth Medical School (www.epistasis.org)

Monday, May 26, 2008

MDR 1.2 Released

We have released version 1.2 of our open-source Multifactor Dimensionality Reduction (MDR) software package. It can be downloaded from here.

This new version includes interaction graphs to complement the existing interaction dendrogram for visualizing interaction information as a way to statistically interpret MDR models and attribute relationships. See our 2006 paper in the Journal of Theoretical Biology for more information about interactions graphs and dendrograms. See also my more recent review in the book Knowledge Discovery and Data Mining (email me for a pdf version). This work is inspired by the excellent work of Dr. Aleks Jakulin. See his list of papers on the topic here.

For more information about MDR please visit www.epistasis.org and www.multifactordimensionalityreduction.org. Also see the November and December 2006 posts on this blog for the MDR 101 tutorial. Let us know if you have any questions, comments or concerns.

We are planning to release MDR 2.0 this summer that will include estimation of distribution algorithms (EDAs) for stochastic searching.