Epistasis Blog

From the Computational Genetics Laboratory at Dartmouth Medical School (www.epistasis.org)

Monday, December 30, 2013

Epistasis Blog Posts from 2013

January, 2013 

Gene-gene interactions in a pathway-based analysis of genetic susceptibility to bladder cancer



Complex effects of nucleotide variants in a mammalian cis-regulatory element



Four tips for success in graduate school and beyond

Gene-based testing of interactions in association studies of quantitative traits

Alternative definitions of epistasis

Role of genetic heterogeneity and epistasis in bladder cancer susceptibility and outcome: a learning classifier system approach

Multifactor dimensionality reduction reveals a three-locus epistatic interaction associated with susceptibility to pulmonary tuberculosis

ViSEN: Methodology and software for visualization of statistical epistasis networks

Statistical epistasis networks reduce the computational complexity of searching three-locus genetic models

An information-gain approach to detecting three-way epistatic interactions in genetic association studies



Things genes can't do. Shall we have pie or stew?



Probabilistic multifactor causation - what do we mean?

Journal impact factors - updated

A robustness study of parametric and non-parametric tests in model-based multifactor dimensionality reduction for epistasis detection



JAMIA special issue on Translational Bioinformatics



A simple extension of Multifactor Dimensionality Reduction (MDR) for detecting epistasis effects on quantitative traits



The effect of genetic background on genetic interaction networks



Genotype-environment interactions reveal causal pathways that mediate genetic effects on phenotype



Best paper award at Translational Bioinformatics Conference



Big data analysis on autopilot?

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